Clinical outcomes of closed-loop vagal nerve stimulation in patients with refractory epilepsy
نویسندگان
چکیده
منابع مشابه
Vagal nerve stimulation for refractory epilepsy: a brief review
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for patients with drugresistance epilepsy. Short and long-term VNS studies demonstrate a seizure-suppressing effect, with a more efficacy in long-term treatment. Precise mechanisms of VNS in attenuating seizure are not fully understood. Clarification of VNS mechanisms of action may improve its clinical efficacy, as it may provid...
متن کاملVagal nerve stimulation in patients with refractory epilepsy. Effect on seizure frequency, severity and quality of life
Vagal nerve stimulation using an NCP (Cyberonics) device has been suggested as a potential treatment for patients with epilepsy that has previously proven refractory. Ten patients in Northern Ireland have had this device implanted and been fully audited pre- and post-operatively. Twelve months post-implantation, five patients have demonstrated a greater than 50% reduction in seizure frequency. ...
متن کاملRespiratory pattern changes in sleep in children on vagal nerve stimulation for refractory epilepsy.
BACKGROUND An altered breathing pattern in sleep, over two to three weeks, reported by the parents of a child on Vagal Nerve Stimulation (VNS) therapy for refractory epilepsy, prompted a sleep study in him. His polysomnography (PSG) revealed respiratory irregularity concordant with VNS activation. Dyspnoea is a well recognised and reported side effect of the VNS. However there are only a few st...
متن کاملVagal nerve stimulation for the treatment of medically refractory epilepsy: a review of the current literature.
OBJECT The authors conducted a study to evaluate the published results of vagal nerve stimulation (VNS) for medically refractory seizures according to evidence-based criteria. METHODS The authors performed a review of available literature published between 1980 and 2010. Inclusion criteria for articles included more than 10 patients evaluated, average follow-up of 1 or more years, inclusion o...
متن کاملVagus nerve stimulation for refractory epilepsy
Vagus nerve stimulation (VNS) is a neurophysiological treatment for patients with medically or surgically refractory epilepsy. Since the first human implant in 1989, more than 10 000 patients have been treated with VNS. Two randomized controlled studies have shown a statistically significant decrease in seizure frequency during a 12-week treatment period versus a baseline period when 'high stim...
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ژورنال
عنوان ژورنال: Seizure
سال: 2019
ISSN: 1059-1311
DOI: 10.1016/j.seizure.2019.07.006